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Similac 360 Total Care Sensitive Infant Formula

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For immune support, brain development, and digestive health
Closest prebiotic blend to breast milk
Exclusive blend of 5 HMO prebiotics
For fussiness and gas due to lactose sensitivity

Similac 360 Total Care Sensitive Ready-To-Feed Infant Formula

Size	32 oz - 1 Bottle Clear

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First Delivery: March 10, 2026 - March 11, 2026

Save 10% now on 1st Autoship*, 5% on repeat orders

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(10% off first Autoship order*)

$17.40

For immune support, brain development, and digestive health
Closest prebiotic blend to breast milk
Exclusive blend of 5 HMO prebiotics
For fussiness and gas due to lactose sensitivity

About Similac 360 Total Care Sensitive Ready-To-Feed Infant Formula

Similac 360 Total Care Sensitive Infant Formula is a gentle nutrition designed to ease typical tummy troubles like fussiness and gas due to lactose sensitivity. The formula has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk and nutrition designed for immune support, brain development, and digestive health.

Key Benefits & Features

Formula breakthrough for sensitive tummies is gentle nutrition designed to ease typical tummy troubles like fussiness and gas due to lactose sensitivity
Similac 360 Total Care Sensitive has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk
Nutrition designed for immune support, brain development, and digestive health
Great for on-the-go and late-night feeding; no mixing required

Similac 360 Total Care Sensitive Ready-To-Feed Infant Formula FAQs

What is Similac 360 Total Care?

Similac 360 Total Care is our newest infant formula, containing 5 HMOs, a prebiotic blend previously only available in breast milk. HMOs are immune-nourishing prebiotics that are structurally identical to those in breast milk.

What is the difference between Similac 360 Total Care and Similac Pro-Advance and Similac Pro-Sensitivewith 2′-FL HMO?

Pro-Advance and Pro-Sensitive have 2′-FL HMO, which represents the fucosylated category of HMOs. There are 3 categories of HMOs that each provide unique benefits to the infant: fucosylated, sialylated, and acetylated. 360 Total Care has 3-FL (fucosylated), LNT (acetylated), 3′-SL (sialylated), and 6′-SL (sialylated), which represent the other categories of HMOs.

Why don’t 360 Total Care formulas contain FOS?

360 Total Care has replaced the prebiotic FOS with 4 additional HMO prebiotics. HMOs are immune-nourishing prebiotics that are structurally identical to those in breast milk. FOS is not found in human milk.

Are the new 360 Total Care formulas better than Pro-Advance and Pro-Sensitive?

Our Pro-Advance and Pro-Sensitive formulas provide complete nutrition for your infant and have 2′-FL HMO. 360 Total Care formulas have 5 HMOs, which make them closer to breast milk with the addition of 4 HMOs.